Vitamin B6 (pyridoxal phosphate)

The active form of vitamin B6, which several hundred enzymes use, including the ones that clear homocysteine.

It is one of the three vitamins homocysteine depends on, so a raised homocysteine is a reason to look here.

This is the vitamin where too much is a real problem: long-term high-dose supplements cause nerve damage, so a high result is worth acting on rather than ignoring. It falls with inflammation independently of intake.

Worth discussing a high value on supplements, especially with tingling in the hands or feet.